Endothelial Small-Conductance and Intermediate-Conductance KCa Channels
نویسندگان
چکیده
منابع مشابه
Role of endothelial intermediate conductance KCa channels in cerebral EDHF-mediated dilations.
The present study evaluated the role of endothelial intermediate conductance calcium-sensitive potassium channels (IKCa) in the mechanism of endothelium-derived hyperpolarizing factor (EDHF)-mediated dilations in pressurized cerebral arteries. Male rat middle cerebral arteries (MCA) were mounted in an isolated vessel chamber, pressurized (85 mmHg), and luminally perfused (100 microl/min). Arter...
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Vascular endothelial cells (EC) are continuously exposed to shear stress associated with the flowing blood. Over the years, it has become clear that such shear exerts a multitude of effects on endothelial biology and vascular function and structure, ranging in time span from seconds to months. On the scale of seconds, shear-dependent vasodilation has been demonstrated in many experimental setti...
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Sheng J-Z, Braun AP. Smalland intermediate-conductance Ca -activated K channels directly control agonist-evoked nitric oxide synthesis in human vascular endothelial cells. Am J Physiol Cell Physiol 293: C458–C467, 2007. First published April 25, 2007; doi:10.1152/ajpcell.00036.2007.—The contribution of small-conductance (SKCa) and intermediate-conductance Ca -activated K (IKCa) channels to the ...
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ژورنال
عنوان ژورنال: Journal of Cardiovascular Pharmacology
سال: 2013
ISSN: 0160-2446
DOI: 10.1097/fjc.0b013e318279ba20